Bcl1 polymorphism of glucocorticoid receptor gene in patients with bronchial asthma with obesity
نویسندگان
چکیده
منابع مشابه
Bcl1 polymorphism of glucocorticoids receptor gene and bronchial asthma.
The aim of our study was to investigate frequencies of alleles and genotypes of Bcl1 GR gene polymorphism and their correlation with prevalence of BA. Study involved 188 patients with BA and 95 healthy individuals. Bcl1 (rs41423247) polymorphism in exon 2 was determined by means of polymerase chain reaction with subsequent RFLP analysis (restriction fragment length polymorphism) by Fleury I. et...
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15 صفحه اولHeterogeneity of Glucocorticoid Resistance in Patients with Bronchial Asthma
Bronchial asthma is assumed to be the result of excessive inflammation driven by an aberrant T-helper-2 (Th2) response. Recently, it has begun to be recognized that asthma is a heterogeneous disorder. Glucocorticoids (GCs) are effective treatment for bronchial asthma; however, the inflammation in bronchial asthma cannot always be fully controlled. A recent study demonstrated a new underlying me...
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ژورنال
عنوان ژورنال: Cytology and Genetics
سال: 2016
ISSN: 0095-4527,1934-9440
DOI: 10.3103/s0095452716030063